Author Archives: snsm

Recent publication from Houston’s lab

IGF-1 Receptor Modulates FoxO1-mediated Tamoxifen Response in Breast Cancer Cells”  Molecular Cancer Research (2017)

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Recent publication from Smirnov

Evolutionary selection growth of two-dimensional materials on polycrystalline substrates. Nature Materials, 2018 (18) 318-322 Abstract There is a demand for the manufacture of two-dimensional (2D) materials with high-quality single crystals of large size. Usually, epitaxial growth is considered the method of choice in preparing single-crystalline thin films, but it requires single-crystal substrates for deposition. Here we…
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Recent publication from Li and Talipov labs

Acid-facilitated product release from a Mo(IV) center: relevance to oxygen atom transfer reactivity of molybdenum oxotransferases, Journal of Biological Inorganic Chemistry 2018 (23) 193–207 Abstract We report that pyridinium ions (HPyr+) accelerate the conversion of [Tp*MoIVOCl(OPMe3)] (1) to [Tp*MoIVOCl(NCCH3)] (2) by 103-fold, affording 2 in near-quantitative yield; Tp* = hydrotris(3,5-dimethyl-1-pyrazolyl)borate. This novel reactivity and the mechanism of this reaction were…
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Recent publication from Lusetti’s Lab

The cohesin-like RecN protein stimulates RecA-mediated recombinational repair of DNA double-strand breaks, Nature Communications 2017 Abstract RecN is a cohesin-like protein involved in DNA double-strand break repair in bacteria. The RecA recombinase functions to mediate repair via homologous DNA strand invasion to form D-loops. Here we provide evidence that the RecN protein stimulates the DNA strand…
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