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- B.S., Chemistry, Pacific University 2005
- Ph. D., Biochemistry and Molecular Biology, Oregon Health and Science University 2009. Advisor: Dr. Pierre Moenne-Loccoz
- Postdoctoral, University of Minnesota, Advisor Dr. Carrie Wilmot
Transition metals such as iron, copper, manganese and zinc serve essential functions in biology and are required for such fundamental processes as respiration, photosynthesis and DNA synthesis among others. My lab is interested in the mechanisms by which bacteria acquire these metals from the environment, and how certain metalloproteins are used as sensors of environmental conditions. These two processes are important for virulence and survival of pathogenic bacteria within the human host. We employ X-ray crystallography as well as various spectroscopic, biophysical, and molecular biology techniques to assess the structure, function and mechanism of proteins involved in these processes. The long-term goal of these studies is to further the development of improved antibiotics against resistant bacteria, which target these metal import and sensory functions.
Awards and Honors
National Research Service Award, National Institutes of Health, 2011-2013 Boyer-Peter Award for Postdoctoral Research, University of Minnesota, 2013
Watch a video of Dr. Yukl discussing his research