Lyons Publications

• Solution Structure of the Grb14-SH2 Domain and Comparison to the Structure and Backbone Relaxation Behavior of the Grb7-SH2/erbB2 Peptide Complex.
  Scharf, P.J.; Ivancic, M.; Guth, E.C.; Witney, J.; Daugherty, M.A.; Lyons, B.A.
  (Submitted to: Proteins: Structure, Function, and Bioinformatics)
• Solution Structure of the Human Grb7-SH2 Domain/erbB2 Peptide Complex and Structural Basis for Grb7 Binding to erbB2.
  Ivancic, M.; Daly, R.J.; Lyons, B.A. (2003)
  J Biomol NMR, Nov;27(3):205-19.
• Assignment of Backbone 1H, 13C, and 15N Resonances of the SH2 Domain of Human Grb14.
  Scharf, P.J.; Lyons B.A. (2002)
  J Biomol NMR, Nov;24(3):275-6.
• Assignment of Backbone 1H, 13C, and 15N Resonances of Human Grb7-SH2 Domain in Complex with a Phosphorylated Peptide Ligand.
  Brescia, P.J.; Ivancic, M.; Lyons, B.A. (2002)
  J Biomol NMR, May;23(1):77-8.
• Spectral and Metal-Binding Properties of Three Single-Point Tryptophan Mutants of Human Transferrin N-Lobe.
  He, Q.Y.; Mason, A.; Lyons, B.; Tam, B.; Nguyen, V.; MacGillivray, R.; Woodworth, R. (2001)
  The Biochemistry Journal 354, 423.
• Uracil Glycol Deoxynucleoside Triphosphate is a Better Substrate for DNA Polymerase I Klenow Fragment than Thymine Glycol Deoxynucleoside Triphosphate.
  Purmal, A.A.; Bond, J.P.; Lyons, B.A.; Kow, Y.W.; & Wallace, S.S. (1998)
  Biochemistry 37(1):330-8.
• Chemical Shift Assignments and Secondary Structure of the Grb2 SH2 Domain by Heteronuclear NMR Spectroscopy.
  Wang, Y.S.; Frederick, A.F.; Senior, M.M.; Lyons, B.A.; Black, S.; Kirschmeier, P.; Perkins, L.M.; & Wilson, O. (1996)
  J Biomol NMR 7(2):89-98.
• The Mechanism of Binding Staphylococcal Protein A to Immunoglobin G Does Not Involve Helix Unwinding.
  Jendeberg, L.; Tashiro, M.; Tejero, R.; Lyons, B.A.; Uhlen, M.; Montelione, G.T.; & Nilsson, B. (1996)
  Biochemistry 35(1):22-31.
• An Improved Strategy for Determining Resonance Assignments for Isotopically Enriched Proteins and Its Application to an Engineered Domain of Staphylococcal Protein A.
  Lyons, B.A.; Tashiro, M.; Cedergren, L.; Nilsson, B.; & Montelione, G.T. (1993)
  Biochemistry 32(31):7839-45.
• A General Approach for Determining Scalar Coupling Constants in Polypeptides and Proteins.
  Montelione, G.T.; Emerson, S.D.; & Lyons, B.A. (1992)
  Biopolymers 32(4):327-34.
• Identification of Novel Therapeutic Targets for Fibrolamellar Carcinoma Using Patient Derived Xenografts and Direct from Patient Screening. Lalazar G, Requena D, Ramos-Espiritu L, *Ng D, Bhola P, de Jong Y, Wang R, Croteau N, Shebl B, Levin S, Michalidis E, Kabbani M, Vercauteren K, Hurley A, Farber B, Hammond W, Saltsman III J, Weinberg E, Glickman J, Lyons B, Ellison J, Schadde E, Hertl M, Leiting J, Truty M, Smoot R, Tierney F, Kato T, Wendel H, LaQuaglia M, Rice C, Letai A, Coffino P, Torbenson M, Ortiz M, and Simon S. Cancer Discov. 2021. PMID: 34127480.
• Disruption of Proteome by an Oncogenic Fusion Kinase Alters Metabolism in Fibrolamellar Hepatocellular Carcinoma. Levin S, Tomasini M, Knox J, Shirani M, Shebl B, Requena D, Alwaseem H, Surjan R, Lahasky R, Molina H, Torbenson M, Lyons B, Migler R, Coffino P, and Simon S. 2023. Sciences Advances (in -press).